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Daxxify vs. Botox: Which One Is Best for You?

When you think about a cosmetic treatment that smooths fine lines and wrinkles, Botox is probably the first thing that comes to mind. This injectable has been the #1 way to slow down the signs of aging for over two decades. Plus, it’s a popular solution for various trending cosmetic treatments like jawline slimming, brow lifts, and non-surgical nose jobs.

However, a Botox alternative has entered the chat. Daxxify is the newest cosmetic injectable to join the neuromodulator family. Also known as Daxi, this neurotoxin was approved by the FDA in 2022 and offers some unique benefits that set it apart from its competitors, longevity being one of them. Daxxify’s ability to last longer than Botox plays a big part in its growing popularity. Thanks to its peptide-powered formulation, Daxi can last twice as long as other neuromodulators, up to 9 months for some patients.

Both injectables deliver benefits that serve different aesthetic needs. The choice is based on personal preferences, aesthetic goals, and budget.

Wondering how Daxxify compares to Botox? Read on to discover the benefits and drawbacks of these two injectables to decide which is the best aesthetic treatment for you.

woman getting botox

What is Botox?

Botox is an injectable neuromodulator that relaxes the muscles in the face, which causes fine lines and wrinkles. This FDA-approved treatment contains a protein called botulinum toxin. It also contains human serum albumin (HSA), a human-derived protein that helps stabilize Botox. When injected, the toxin blocks the signals from the nerves to the active muscles, temporarily restricting their movement. This results in a smoother, more rejuvenated appearance and prevents deeper wrinkles like crow’s feet, frown lines, and forehead lines from forming.

What is Daxxify?

Daxxify is a neurotoxin treatment similar to Botox, Dysport, and other competitors. This injectable is FDA-approved to treat frown lines or glabellar lines (11’s between the brows), and delivers a smoother, more rejuvenated appearance. This new neurotoxin, also known as daxibotulinumtoxinA-lanm or Daxi, is formulated without human serum albumin and animal-based components. Instead, it uses peptide exchange technology to deliver botulinum toxin and paralyze active muscle movement. This prevents wrinkles from forming and temporarily enhances moderate to severe frown lines.

Benefits of Botox vs. Daxxify

woman having botox treatment

Botox and Daxi are both great options for reducing wrinkles and fine lines. They are safe and effective and can give you the youthful and refreshed appearance you desire. While Botox is a well-established cosmetic treatment, Daxxify is making waves thanks to its impressive results. Keep reading to learn more about the benefits of each and find out how they compare.

Botox Benefits

Daxxify Benefits

One of the biggest benefits of Daxxify is its longevity. The effects of Daxi can last up to 9 months, longer than any other neurotoxin treatment on the market. As a result, Daxxify can save you time and money as you do not need to go in for injections as often as Botox. Additionally, many individuals experience a stronger pull or “freeze” with Daxi compared to Botox.

Other Uses of Botox

In addition to eliminating wrinkles and smoothing the appearance, Botox is also considered safe for different cosmetic and non-cosmetic treatments. These include:

Daxxify vs. Botox FAQs

Is Botox Safe?

Thanks to rigorous testing and research since it was first FDA-approved to treat forehead wrinkles in 2002, Botox has established a reputation as a safe and effective solution to reduce wrinkles and fine lines.

In a study published in the Journal of the American Academy of Dermatology, researchers found that Botox injections are well-tolerated by patients and have a low risk of adverse reactions. In another Clinical Interventions in Aging study, researchers found that Botox injections effectively reduced wrinkles and had a high patient satisfaction rate. The study also found that Botox had a low risk of complications when administered by a qualified healthcare provider.

How Safe is Daxxify?

Daxxify was FDA-approved in 2022 and has a well-established safety profile. Studies show that Daxxify is a safe Botox alternative that effectively combats the signs of aging by treating moderate to severe glabellar lines.

Daxxify’s safety is examined in a 2023 clinical trial by the Department of Dermatology at Yale University School of Medicine. The study supports Daxi’s improved efficacy, safety, and prolonged effectiveness as a peptide-based neuromodulator. Additionally, the study found that adverse reactions, such as bruising or headaches, were mild.

Longevity of Daxxify vs. Botox

beautiful woman smiling in a mirror

The effects of Botox and Daxxify are not permanent and require follow-up treatments to maintain results. In terms of longevity, Daxxify has been shown to last longer than Botox. Currently, Botox lasts about 3-4 months for most patients. Based on clinical trials examining Daxxify’s longevity, the average duration was 6 months, with results lasting as long as 9 months in some patients.

Daxi’s longevity is due to its unique peptide technology. The special protein in Daxi makes the active portion of the drug stickier where the nerve and muscle meet. This contributes to Daxxify’s longevity by extending the paralyzing effects of the injectable on the muscle.
Genetic and lifestyle factors can impact the longevity of neurotoxins like Daxxify and Botox. Metabolism, facial expressions, sun exposure, and other lifestyle choices also affect the duration of effects.

How Much Is Daxxify vs. Botox?

Since Daxxify is longer-lasting than Botox, it tends to cost more. Daxxify is about $10-$15 more per unit than Botox. Also, remember that 1 unit of Botox = 2 units of Daxxify. Additionally, the provider, the location, and the amount of product you need will impact the total treatment cost.

What Happens If You Stop Using Daxxify or Botox?

If you stop getting Daxxify or Botox injections, your wrinkles and fine lines will return. A popular misconception is that if you stop getting Daxxify or Botox, your face will start to droop, or your wrinkles will be worse than they were before you started using neurotoxins. However, this is not true.

Potential Side Effects of Daxxify vs. Botox

Getting neuromodulator treatments like Botox and Daxxify comes with common side effects such as slight bruising, discoloration, and swelling at the injection site. Additional potential side effects include:

On rare occasions, Daxxify and Botox can spread to other parts of the body, causing potential side effects such as muscle weakness or blurred vision. As with any aesthetic treatment, individual experiences can vary. A skilled medical practitioner can minimize these risks through proper administration.

Defy the Signs of Aging with Daxxify and Botox in Naperville, Illinois

If you are ready to slow the signs of aging and smooth your skin by reducing fine lines and wrinkles, Daxxify and Botox are amazing options. Contact Sante Medical Aesthetics to learn more about these two high-performing injectables.

We are the top provider of neurotoxin treatments in Naperville, Illinois, and surrounding Chicago neighborhoods. Give us a call at (630) 586-6244 to secure your complimentary consultation with one of our expert injectors and find out which injectable is right for you. We can’t wait to share more about how Botox and Daxxify can enhance your beauty and help you achieve a smooth and flawless appearance.

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